Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Mnod_5243PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: mpo:Mpop_2047 methyl-accepting chemotaxis sensory transducer. (562 aa)    
Predicted Functional Partners:
Mnod_1691
CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: met:M446_4838 CheA signal transduction histidine kinase.
 
 0.994
Mnod_5453
CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: met:M446_0244 CheA signal transduction histidine kinase.
 
 0.994
Mnod_0766
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: met:M446_2049 CheA signal transduction histidine kinase.
 
 0.991
Mnod_1695
PFAM: MCP methyltransferase CheR-type; KEGG: met:M446_4834 MCP methyltransferase, CheR-type.
 
 0.983
Mnod_5450
PFAM: MCP methyltransferase CheR-type; KEGG: met:M446_0241 MCP methyltransferase, CheR-type.
 
 0.983
Mnod_0764
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.982
Mnod_1692
PFAM: CheW domain protein; KEGG: met:M446_4837 CheW protein.
 
 0.981
Mnod_0761
PFAM: CheW domain protein; KEGG: met:M446_2054 CheW protein.
 
 0.979
Mnod_3755
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; KEGG: met:M446_6211 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor.
 
 0.975
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.942
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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