Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_5319KEGG: met:M446_5015 hypothetical protein. (238 aa)    
Predicted Functional Partners:
Mnod_5320
PFAM: aspartate/glutamate/uridylate kinase; KEGG: met:M446_5016 aspartate/glutamate/uridylate kinase.
 
   
 0.966
Mnod_5321
PFAM: dihydropteroate synthase DHPS; KEGG: met:M446_5017 dihydropteroate synthase DhpS.
 
     0.917
Mnod_5322
PFAM: protein of unknown function DUF447; KEGG: met:M446_5018 hypothetical protein.
 
     0.917
Mnod_5318
KEGG: met:M446_5014 hypothetical protein.
       0.853
Mnod_6000
KEGG: met:M446_5776 tungsten-containing formylmethanofuran dehydrogenase, subunit B.
 
   
 0.831
Mnod_5999
TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3; KEGG: met:M446_5775 formylmethanofuran dehydrogenase subunit A.
 
   
 0.815
Mnod_6009
TIGRFAM: H4MPT-linked C1 transfer pathway protein; KEGG: met:M446_5788 H4MPT-linked C1 transfer pathway protein.
 
   
 0.808
Mnod_5997
TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase alpha subunit domain protein; KEGG: met:M446_5773 formylmethanofuran dehydrogenase subunit C.
 
     0.792
ffsA
Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.
 
     0.792
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
     0.792
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: low (28%) [HD]