Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (315 aa)    
Predicted Functional Partners:
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
 0.998
argD
TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: met:M446_6536 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.993
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
  
 0.964
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: met:M446_5988 argininosuccinate lyase.
 
  
 0.955
arcB
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.947
argG
PFAM: argininosuccinate synthase; KEGG: met:M446_6641 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.940
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: met:M446_3399 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
 
  
 0.808
Mnod_3650
TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: rec:RHECIAT_PC0000539 acetylornithine deacetylase protein.
  
 
 0.801
Mnod_7452
TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: met:M446_6541 acetylornithine deacetylase (ArgE).
  
 
 0.801
Mnod_5338
PFAM: protein of unknown function DUF1348; KEGG: met:M446_5027 hypothetical protein.
       0.775
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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