STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_5341TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: met:M446_5035 BadM/Rrf2 family transcriptional regulator. (167 aa)    
Predicted Functional Partners:
Mnod_5342
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
       0.834
Mnod_7171
KEGG: met:M446_6321 NifU domain-containing protein.
  
  
 0.828
Mnod_0643
PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: aba:Acid345_2275 aminotransferase, class V.
 
  
 0.818
Mnod_5849
PFAM: aminotransferase class V; KEGG: met:M446_5110 aminotransferase class V.
 
  
 0.818
Mnod_3325
TIGRFAM: FeS assembly scaffold SufA; iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: met:M446_4331 FeS assembly scaffold SufA; Belongs to the HesB/IscA family.
 
  
 0.815
Mnod_2864
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
   
 0.582
Mnod_5340
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: met:M446_5034 response regulator receiver modulated metal dependent phosphohydrolase.
       0.564
Mnod_3988
PFAM: NifQ family protein; KEGG: met:M446_3543 NifQ family protein.
  
  
 0.527
Mnod_0728
PFAM: Chorismate mutase; KEGG: met:M446_1107 chorismate mutase.
  
   
 0.496
Mnod_6438
MOSC domain containing protein; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; 3-alpha domain protein; MOSC domain containing protein; Oxidoreductase FAD-binding domain protein; KEGG: rle:pRL110471 putative flavoprotein/ferredoxin.
  
  
 0.495
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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