Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Mnod_5423PFAM: Glutathione S-transferase domain; KEGG: met:M446_0214 glutathione S-transferase domain-containing protein. (230 aa)    
Predicted Functional Partners:
Mnod_4666
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
   
 0.943
gshB
TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; KEGG: met:M446_1113 glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
 
  
 0.930
Mnod_6935
Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 
 0.903
Mnod_5421
KEGG: met:M446_0212 NAD-dependent epimerase/dehydratase.
 
   0.860
Mnod_5422
PFAM: domain of unknown function DUF1730; KEGG: mpo:Mpop_2342 protein of unknown function DUF1730.
       0.853
Mnod_4445
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
  
  
  0.728
Mnod_1610
TIGRFAM: double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; KEGG: met:M446_0489 double-strand break repair helicase AddA; Belongs to the helicase family. UvrD subfamily.
  
     0.719
Mnod_0379
PFAM: protein of unknown function DUF1058; KEGG: met:M446_2231 hypothetical protein.
  
    0.708
Mnod_5968
KEGG: met:M446_5200 hypothetical protein; Belongs to the UPF0335 family.
  
     0.706
Mnod_6012
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
  
  
  0.705
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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