Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_5444PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: met:M446_0236 short-chain dehydrogenase/reductase SDR. (255 aa)    
Predicted Functional Partners:
Mnod_5445
PFAM: AMP-dependent synthetase and ligase; KEGG: met:M446_0237 AMP-dependent synthetase and ligase.
 
   0.780
Mnod_5442
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: met:M446_0234 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.710
Mnod_5443
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: met:M446_0235 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 
 0.628
Mnod_5441
TIGRFAM: pimeloyl-CoA dehydrogenase, large subunit; PFAM: acyl-CoA dehydrogenase domain protein; KEGG: met:M446_0233 pimeloyl-CoA dehydrogenase, large subunit.
 
  0.616
Mnod_5440
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: met:M446_0232 acyl-CoA dehydrogenase domain-containing protein.
 
  0.574
Mnod_4413
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: met:M446_3408 acyl-CoA dehydrogenase domain-containing protein.
 
  0.573
Mnod_1945
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: met:M446_0317 beta-ketoacyl synthase.
  
 
 0.510
Mnod_4641
PFAM: MaoC domain protein dehydratase; KEGG: met:M446_2586 dehydratase.
 
 0.473
Mnod_4490
PFAM: aminoglycoside phosphotransferase; KEGG: met:M446_4558 aminoglycoside phosphotransferase.
 
 
 0.472
Mnod_1232
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mpt:Mpe_A0908 short chain dehydrogenase/reductase family oxidoreductase.
 
    0.450
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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