Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_5453CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: met:M446_0244 CheA signal transduction histidine kinase. (747 aa)    
Predicted Functional Partners:
Mnod_3755
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; KEGG: met:M446_6211 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor.
 
 0.999
cheB-3
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.999
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.998
Mnod_1691
CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: met:M446_4838 CheA signal transduction histidine kinase.
 
0.998
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.998
Mnod_3756
PFAM: CheB methylesterase; KEGG: mrd:Mrad2831_6263 CheB methylesterase.
 
 0.998
Mnod_5449
PFAM: CheW domain protein; KEGG: met:M446_0240 CheW protein.
 
 0.998
Mnod_5451
PFAM: CheW domain protein; KEGG: mex:Mext_2837 CheW domain-containing protein.
 
 0.998
Mnod_0761
PFAM: CheW domain protein; KEGG: met:M446_2054 CheW protein.
 
 0.997
Mnod_1692
PFAM: CheW domain protein; KEGG: met:M446_4837 CheW protein.
 
 0.997
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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