| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACMD2_05981 | ACMD2_08972 | A0A199VS92 | A0A199V8Z8 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | SP-RING-type domain-containing protein. | 0.784 |
| ACMD2_05981 | ACMD2_13673 | A0A199VS92 | A0A199W0M0 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.543 |
| ACMD2_05981 | ACMD2_16488 | A0A199VS92 | A0A199UI66 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | SUMO-conjugating enzyme SCE1; Belongs to the ubiquitin-conjugating enzyme family. | 0.925 |
| ACMD2_05981 | ACMD2_18646 | A0A199VS92 | A0A199UPC3 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.851 |
| ACMD2_05981 | ACMD2_19874 | A0A199VS92 | A0A199W439 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. | 0.683 |
| ACMD2_05981 | ACMD2_20617 | A0A199VS92 | A0A199UJ11 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | SUMO-activating enzyme subunit 1B-2. | 0.618 |
| ACMD2_05981 | ACMD2_24110 | A0A199VS92 | A0A199VEX4 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | E3 SUMO-protein ligase MMS21. | 0.435 |
| ACMD2_05981 | ACMD2_26802 | A0A199VS92 | A0A199UPB7 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | E3 SUMO-protein ligase MMS21. | 0.435 |
| ACMD2_08972 | ACMD2_05981 | A0A199V8Z8 | A0A199VS92 | SP-RING-type domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.784 |
| ACMD2_08972 | ACMD2_13673 | A0A199V8Z8 | A0A199W0M0 | SP-RING-type domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.784 |
| ACMD2_08972 | ACMD2_16488 | A0A199V8Z8 | A0A199UI66 | SP-RING-type domain-containing protein. | SUMO-conjugating enzyme SCE1; Belongs to the ubiquitin-conjugating enzyme family. | 0.898 |
| ACMD2_08972 | ACMD2_18646 | A0A199V8Z8 | A0A199UPC3 | SP-RING-type domain-containing protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.773 |
| ACMD2_08972 | ACMD2_19874 | A0A199V8Z8 | A0A199W439 | SP-RING-type domain-containing protein. | SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. | 0.702 |
| ACMD2_08972 | ACMD2_20617 | A0A199V8Z8 | A0A199UJ11 | SP-RING-type domain-containing protein. | SUMO-activating enzyme subunit 1B-2. | 0.595 |
| ACMD2_08972 | ACMD2_24110 | A0A199V8Z8 | A0A199VEX4 | SP-RING-type domain-containing protein. | E3 SUMO-protein ligase MMS21. | 0.867 |
| ACMD2_08972 | ACMD2_26802 | A0A199V8Z8 | A0A199UPB7 | SP-RING-type domain-containing protein. | E3 SUMO-protein ligase MMS21. | 0.867 |
| ACMD2_11369 | ACMD2_16488 | A0A199VAE2 | A0A199UI66 | RAN GTPase-activating protein 1. | SUMO-conjugating enzyme SCE1; Belongs to the ubiquitin-conjugating enzyme family. | 0.917 |
| ACMD2_11369 | ACMD2_19874 | A0A199VAE2 | A0A199W439 | RAN GTPase-activating protein 1. | SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. | 0.566 |
| ACMD2_11369 | ACMD2_20617 | A0A199VAE2 | A0A199UJ11 | RAN GTPase-activating protein 1. | SUMO-activating enzyme subunit 1B-2. | 0.621 |
| ACMD2_13673 | ACMD2_05981 | A0A199W0M0 | A0A199VS92 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.543 |