Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACMD2_16488SUMO-conjugating enzyme SCE1; Belongs to the ubiquitin-conjugating enzyme family. (132 aa)    
Predicted Functional Partners:
ACMD2_19874
SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.
   
 0.968
ACMD2_20617
SUMO-activating enzyme subunit 1B-2.
  
 0.965
ACMD2_26802
E3 SUMO-protein ligase MMS21.
    
 0.939
ACMD2_24110
E3 SUMO-protein ligase MMS21.
    
 0.939
ACMD2_05981
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.925
ACMD2_13673
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.925
ACMD2_19844
RAN GTPase-activating protein 1.
    
 0.917
ACMD2_11369
RAN GTPase-activating protein 1.
    
 0.917
ACMD2_18646
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 0.898
ACMD2_08972
SP-RING-type domain-containing protein.
    
 0.898
Your Current Organism:
Ananas comosus
NCBI taxonomy Id: 4615
Other names: A. comosus, Ananas comosus var. comosus, Ananas lucidus, pineapple
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