STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACMD2_01952Pre-mRNA-processing factor 39. (541 aa)    
Predicted Functional Partners:
ACMD2_10595
Splicing factor 3B subunit 1.
   
 
 0.979
ACMD2_05769
U2 small nuclear ribonucleoprotein A.
    
 
 0.955
ACMD2_02844
Small nuclear ribonucleoprotein-associated protein B.
    
 
 0.954
ACMD2_14409
RNA-binding protein 25.
   
 
 0.944
ACMD2_21935
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
   
 
 0.934
ACMD2_21792
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
   
 
 0.934
ACMD2_00364
Cell division cycle 5-like protein.
   
 
 0.928
ACMD2_11262
Nuclear cap-binding protein subunit 1.
    
 
 0.927
ACMD2_02413
DEAD-box ATP-dependent RNA helicase 42.
    
 
 0.915
ACMD2_11244
Small nuclear ribonucleoprotein Sm D1; Involved in splicing regulation. Facilitates post- transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS. Does not participate in the production of small RNAs. Belongs to the snRNP core protein family.
    
 
 0.914
Your Current Organism:
Ananas comosus
NCBI taxonomy Id: 4615
Other names: A. comosus, Ananas comosus var. comosus, Ananas lucidus, pineapple
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.