STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMSG_04114Poly [ADP-ribose] polymerase. (331 aa)    
Predicted Functional Partners:
AMSG_07704
Poly(Adp-ribose) glycohydrolase.
  
 
 0.730
AMSG_04889
Poly(ADP-ribose) glycohydrolase isoform.
  
 
 0.724
AMSG_11440
Uncharacterized protein.
    
  0.603
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.599
AMSG_06760
Histone H2A.
 
  
 
 0.597
AMSG_07825
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.582
AMSG_05189
Breast cancer type 2 susceptibility protein.
    
 0.573
AMSG_03314
Small ubiquitin modifier 2.
   
 0.572
AMSG_00634
SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.572
AMSG_04204
DNA damage-binding protein 2.
    
 0.563
Your Current Organism:
Thecamonas trahens
NCBI taxonomy Id: 461836
Other names: Amastigomonas sp. ATCC 50062, T. trahens ATCC 50062, Thecamonas trahens ATCC 50062
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.