AMSG_04841 protein (Thecamonas trahens) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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protein homology

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Score

AMSG_04841

Long-chain-fatty-acid-CoA ligase 3. (437 aa)

Predicted Functional Partners:

AMSG_06858

0.757

AMSG_08042

0.709

AMSG_02163

0.691

AMSG_09083

0.684

AMSG_05277

0.672

AMSG_01801

0.672

AMSG_09712

0.659

AMSG_03768

0.654

AMSG_01295

0.654

AMSG_08639

0.651

Your Current Organism:

Thecamonas trahens

NCBI taxonomy Id: 461836
Other names: Amastigomonas sp. ATCC 50062, T. trahens ATCC 50062, Thecamonas trahens ATCC 50062

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMSG_01295	AMSG_01801	A0A0L0DMV7	A0A0L0DVH2	Uncharacterized protein.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.494
AMSG_01295	AMSG_02163	A0A0L0DMV7	A0A0L0DVF4	Uncharacterized protein.	Sterol-binding domain-containing protein.	0.734
AMSG_01295	AMSG_04841	A0A0L0DMV7	A0A0L0D7M5	Uncharacterized protein.	Long-chain-fatty-acid-CoA ligase 3.	0.654
AMSG_01295	AMSG_05277	A0A0L0DMV7	A0A0L0DAB3	Uncharacterized protein.	Triacylglycerol lipase.	0.494
AMSG_01295	AMSG_06858	A0A0L0DMV7	A0A0L0DDZ7	Uncharacterized protein.	Long-chain-fatty-acid-CoA ligase ACSBG2.	0.529
AMSG_01295	AMSG_08042	A0A0L0DMV7	A0A0L0DJU2	Uncharacterized protein.	ATP/NADPH-dependent carboxylic acid reductase.	0.529
AMSG_01801	AMSG_01295	A0A0L0DVH2	A0A0L0DMV7	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Uncharacterized protein.	0.494
AMSG_01801	AMSG_02163	A0A0L0DVH2	A0A0L0DVF4	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Sterol-binding domain-containing protein.	0.511
AMSG_01801	AMSG_03768	A0A0L0DVH2	A0A0L0D4T1	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Fatty acid synthase.	0.494
AMSG_01801	AMSG_04841	A0A0L0DVH2	A0A0L0D7M5	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Long-chain-fatty-acid-CoA ligase 3.	0.672
AMSG_01801	AMSG_06858	A0A0L0DVH2	A0A0L0DDZ7	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Long-chain-fatty-acid-CoA ligase ACSBG2.	0.520
AMSG_01801	AMSG_08042	A0A0L0DVH2	A0A0L0DJU2	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	ATP/NADPH-dependent carboxylic acid reductase.	0.520
AMSG_01801	AMSG_09083	A0A0L0DVH2	A0A0L0DLJ4	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	PNPLA domain-containing protein.	0.755
AMSG_01801	AMSG_09712	A0A0L0DVH2	A0A0L0DP47	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	Esterase/lipase/thioesterase family active site protein.	0.716
AMSG_02163	AMSG_01295	A0A0L0DVF4	A0A0L0DMV7	Sterol-binding domain-containing protein.	Uncharacterized protein.	0.734
AMSG_02163	AMSG_01801	A0A0L0DVF4	A0A0L0DVH2	Sterol-binding domain-containing protein.	Lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.511
AMSG_02163	AMSG_03768	A0A0L0DVF4	A0A0L0D4T1	Sterol-binding domain-containing protein.	Fatty acid synthase.	0.734
AMSG_02163	AMSG_04841	A0A0L0DVF4	A0A0L0D7M5	Sterol-binding domain-containing protein.	Long-chain-fatty-acid-CoA ligase 3.	0.691
AMSG_02163	AMSG_05277	A0A0L0DVF4	A0A0L0DAB3	Sterol-binding domain-containing protein.	Triacylglycerol lipase.	0.511
AMSG_02163	AMSG_06858	A0A0L0DVF4	A0A0L0DDZ7	Sterol-binding domain-containing protein.	Long-chain-fatty-acid-CoA ligase ACSBG2.	0.701

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Network Stats

number of nodes:

11

number of edges:

33

average node degree:

6

avg. local clustering coefficient:

0.923

expected number of edges:

11

PPI enrichment p-value:

1.22e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009064

Glutamine family amino acid metabolic process

9 of 56

1.78

4.02

1.34e-12

GO:0006536

Glutamate metabolic process

6 of 17

2.12

3.96

2.46e-09

GO:0019557

Histidine catabolic process to glutamate and formate

4 of 4

2.57

3.44

3.09e-07

GO:0019556

Histidine catabolic process to glutamate and formamide

4 of 4

2.57

3.44

3.09e-07

GO:0043648

Dicarboxylic acid metabolic process

7 of 58

1.65

2.82

1.00e-08

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2561

Histidine metabolism

4 of 5

2.47

2.89

3.30e-06

CL:1242

Arginine biosynthesis, and Glycine catabolic process

5 of 30

1.79

2.26

7.03e-06

CL:1243

Alanine, aspartate and glutamate metabolism, and Glycine catabolic process

4 of 18

1.92

2.06

4.70e-05

CL:1244

Mixed, incl. Ammonia ligase activity, and Glycine catabolic process

3 of 13

1.93

1.52

0.00093

CL:1248

Glutamine synthetase, glycine-rich site, and Acetylation

2 of 5

2.17

1.03

0.0117

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

amah00250

Alanine, aspartate and glutamate metabolism

7 of 30

1.94

4.07

8.75e-11

amah00340

Histidine metabolism

4 of 16

1.97

2.51

4.55e-06

amah00220

Arginine biosynthesis

3 of 20

1.75

1.5

0.00064

amah01100

Metabolic pathways

11 of 547

0.88

0.99

1.36e-08

amah01230

Biosynthesis of amino acids

4 of 95

1.2

0.97

0.0019

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0369

Histidine metabolism

4 of 4

2.57

3.36

4.45e-07

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