STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMSG_06341Fimbrin. (1755 aa)    
Predicted Functional Partners:
AMSG_05306
Twinfilin.
     
 0.830
AMSG_11924
Uncharacterized protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.705
AMSG_10026
Rho GTPase.
   
 
 0.608
AMSG_05368
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.593
AMSG_03466
Actin-like protein 3; Belongs to the actin family.
   
 
 0.590
AMSG_08529
Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
    
 
 0.563
AMSG_03530
Calponin.
    
 
 0.529
AMSG_05462
Flagellar associated protein.
    
 
 0.529
AMSG_06949
Uncharacterized protein.
    
 0.524
AMSG_11985
Uncharacterized protein.
    
 0.524
Your Current Organism:
Thecamonas trahens
NCBI taxonomy Id: 461836
Other names: Amastigomonas sp. ATCC 50062, T. trahens ATCC 50062, Thecamonas trahens ATCC 50062
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.