AMSG_09546 protein (Thecamonas trahens) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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protein homology

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Score

AMSG_09546

Lysophosphatidylcholine acyltransferase 2. (579 aa)

Predicted Functional Partners:

AMSG_11216

0.774

AMSG_01883

0.729

AMSG_03218

0.702

AMSG_10783

0.672

AMSG_03782

0.669

AMSG_11183

0.669

AMSG_08460

0.656

AMSG_07855

0.646

AMSG_10310

0.646

AMSG_08934

0.639

Your Current Organism:

Thecamonas trahens

NCBI taxonomy Id: 461836
Other names: Amastigomonas sp. ATCC 50062, T. trahens ATCC 50062, Thecamonas trahens ATCC 50062

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMSG_01883	AMSG_03218	A0A0L0DTG9	A0A0L0D648	GP-PDE domain-containing protein.	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase.	0.888
AMSG_01883	AMSG_07855	A0A0L0DTG9	A0A0L0DHS8	GP-PDE domain-containing protein.	PNPLA7 protein.	0.917
AMSG_01883	AMSG_08460	A0A0L0DTG9	A0A0L0DK06	GP-PDE domain-containing protein.	Phospholipase D.	0.502
AMSG_01883	AMSG_08934	A0A0L0DTG9	A0A0L0DN24	GP-PDE domain-containing protein.	Group XIIA secretory phospholipase A2.	0.806
AMSG_01883	AMSG_09546	A0A0L0DTG9	A0A0L0DNL0	GP-PDE domain-containing protein.	Lysophosphatidylcholine acyltransferase 2.	0.729
AMSG_01883	AMSG_10310	A0A0L0DTG9	A0A0L0DPV4	GP-PDE domain-containing protein.	HAD superfamily (Subfamily IIIA) phosphatase.	0.804
AMSG_01883	AMSG_11183	A0A0L0DTG9	A0A0L0DUJ0	GP-PDE domain-containing protein.	Phospholipase D.	0.656
AMSG_01883	AMSG_11216	A0A0L0DTG9	A0A0L0DW84	GP-PDE domain-containing protein.	Mboat2 protein; Belongs to the membrane-bound acyltransferase family.	0.812
AMSG_03218	AMSG_01883	A0A0L0D648	A0A0L0DTG9	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase.	GP-PDE domain-containing protein.	0.888
AMSG_03218	AMSG_08460	A0A0L0D648	A0A0L0DK06	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase.	Phospholipase D.	0.604
AMSG_03218	AMSG_09546	A0A0L0D648	A0A0L0DNL0	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase.	Lysophosphatidylcholine acyltransferase 2.	0.702
AMSG_03218	AMSG_10310	A0A0L0D648	A0A0L0DPV4	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase.	HAD superfamily (Subfamily IIIA) phosphatase.	0.883
AMSG_03218	AMSG_11183	A0A0L0D648	A0A0L0DUJ0	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase.	Phospholipase D.	0.643
AMSG_03218	AMSG_11216	A0A0L0D648	A0A0L0DW84	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase.	Mboat2 protein; Belongs to the membrane-bound acyltransferase family.	0.789
AMSG_03782	AMSG_08460	A0A0L0D7R6	A0A0L0DK06	Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.	Phospholipase D.	0.649
AMSG_03782	AMSG_08934	A0A0L0D7R6	A0A0L0DN24	Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.	Group XIIA secretory phospholipase A2.	0.751
AMSG_03782	AMSG_09546	A0A0L0D7R6	A0A0L0DNL0	Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.	Lysophosphatidylcholine acyltransferase 2.	0.669
AMSG_03782	AMSG_11183	A0A0L0D7R6	A0A0L0DUJ0	Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.	Phospholipase D.	0.785
AMSG_03782	AMSG_11216	A0A0L0D7R6	A0A0L0DW84	Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.	Mboat2 protein; Belongs to the membrane-bound acyltransferase family.	0.814
AMSG_07855	AMSG_01883	A0A0L0DHS8	A0A0L0DTG9	PNPLA7 protein.	GP-PDE domain-containing protein.	0.917

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Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.832

expected number of edges:

24

PPI enrichment p-value:

0.814

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009847

Spore germination

9 of 60

1.89

4.57

2.71e-13

GO:0030154

Cell differentiation

11 of 230

1.39

2.6

4.84e-13

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

10 of 1434

0.55

0.44

0.0013

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6158

Mixed, incl. Spore germination GerAB, and Spore germination GerAC-like

6 of 10

2.49

5.36

2.04e-11

CL:5985

Spore germination, and Sporulation

11 of 102

1.74

4.55

1.56e-16

CL:6160

Spore germination GerAB, and Spore germination GerAC-like

4 of 5

2.61

3.58

1.75e-07

CL:5988

Spore germination, and Sporulation

5 of 77

1.52

1.72

3.85e-05

CL:6051

SpoVA, and Spore wall

2 of 5

2.31

1.13

0.0082

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF05504

Spore germination B3/ GerAC like, C-terminal

4 of 16

2.11

2.27

2.95e-05

PF03845

Spore germination protein

3 of 19

1.91

1.26

0.0033

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR046953

Spore germination GerAC-like, C-terminal

4 of 16

2.11

2.08

7.51e-05

IPR038501

Spore germination GerAC, C-terminal domain superfamily

4 of 16

2.11

2.08

7.51e-05

IPR008844

Spore germination GerAC-like

4 of 16

2.11

2.08

7.51e-05

IPR004761

Spore germination GerAB

3 of 18

1.93

1.25

0.0036

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