STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMSG_10860Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (470 aa)    
Predicted Functional Partners:
AMSG_02107
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.897
AMSG_02895
Dihydrolipoamide succinyltransferase.
 
 0.853
AMSG_00665
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.853
AMSG_07252
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.848
AMSG_02297
2-oxoisovalerate dehydrogenase subunit beta.
 
 0.848
AMSG_03204
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
 
 0.837
AMSG_06696
Glutathione S-transferase domain-containing protein; Belongs to the GST superfamily.
   
 
 0.817
AMSG_06205
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 
 0.792
AMSG_00015
Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component.
  
 0.785
AMSG_12229
Uncharacterized protein.
  
 0.785
Your Current Organism:
Thecamonas trahens
NCBI taxonomy Id: 461836
Other names: Amastigomonas sp. ATCC 50062, T. trahens ATCC 50062, Thecamonas trahens ATCC 50062
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