STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMSG_11356Mercuric transporter periplasmic component. (767 aa)    
Predicted Functional Partners:
AMSG_02107
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.969
AMSG_07252
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.960
AMSG_02895
Dihydrolipoamide succinyltransferase.
 
 0.956
AMSG_00665
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.919
AMSG_00116
Pyruvate dehydrogenase E1 component subunit alpha.
 
 
 0.913
AMSG_12229
Uncharacterized protein.
  
 0.898
AMSG_02297
2-oxoisovalerate dehydrogenase subunit beta.
 
 0.895
AMSG_12225
Uncharacterized protein; Belongs to the complex I 75 kDa subunit family.
  
 0.876
AMSG_07852
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.871
AMSG_00015
Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component.
  
 0.853
Your Current Organism:
Thecamonas trahens
NCBI taxonomy Id: 461836
Other names: Amastigomonas sp. ATCC 50062, T. trahens ATCC 50062, Thecamonas trahens ATCC 50062
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.