STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEK61198.1Threonine dehydratase. (403 aa)    
Predicted Functional Partners:
SEK20666.1
Threonine synthase.
  
 
 0.985
SEK52891.1
Acetolactate synthase, small subunit.
  
 
 0.982
SEK95729.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.979
SEK19650.1
Branched-chain amino acid aminotransferase.
  
 
 0.969
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.967
SEK97788.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 0.957
SEK86609.1
L-threonine aldolase.
   
 
 0.954
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.952
trpB
Phosphoribosylanthranilate isomerase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpF family.
  
 0.946
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.939
Your Current Organism:
Pseudobutyrivibrio ruminis
NCBI taxonomy Id: 46206
Other names: DSM 9787, P. ruminis, strain A12-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.