node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEK30384.1 | SEK65935.1 | SAMN02910377_00519 | SAMN02910377_01471 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.997 |
SEK30384.1 | SEK97332.1 | SAMN02910377_00519 | SAMN02910377_02326 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | Phosphoribosylformylglycinamidine synthase. | 0.999 |
SEK30384.1 | guaA | SAMN02910377_00519 | SAMN02910377_00268 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.957 |
SEK30384.1 | guaB | SAMN02910377_00519 | SAMN02910377_02287 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.994 |
SEK30384.1 | purC | SAMN02910377_00519 | SAMN02910377_01473 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.992 |
SEK30384.1 | purD | SAMN02910377_00519 | SAMN02910377_01221 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.992 |
SEK30384.1 | purE | SAMN02910377_00519 | SAMN02910377_01218 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.963 |
SEK30384.1 | purF | SAMN02910377_00519 | SAMN02910377_01472 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.985 |
SEK30384.1 | purM | SAMN02910377_00519 | SAMN02910377_01219 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.984 |
SEK30384.1 | purN | SAMN02910377_00519 | SAMN02910377_01220 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | Phosphoribosylglycinamide formyltransferase-1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
SEK65935.1 | SEK30384.1 | SAMN02910377_01471 | SAMN02910377_00519 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.997 |
SEK65935.1 | SEK97332.1 | SAMN02910377_01471 | SAMN02910377_02326 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase. | 0.999 |
SEK65935.1 | guaA | SAMN02910377_01471 | SAMN02910377_00268 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.947 |
SEK65935.1 | guaB | SAMN02910377_01471 | SAMN02910377_02287 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.947 |
SEK65935.1 | purC | SAMN02910377_01471 | SAMN02910377_01473 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.998 |
SEK65935.1 | purD | SAMN02910377_01471 | SAMN02910377_01221 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.982 |
SEK65935.1 | purE | SAMN02910377_01471 | SAMN02910377_01218 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.974 |
SEK65935.1 | purF | SAMN02910377_01471 | SAMN02910377_01472 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.988 |
SEK65935.1 | purM | SAMN02910377_01471 | SAMN02910377_01219 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.951 |
SEK65935.1 | purN | SAMN02910377_01471 | SAMN02910377_01220 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase-1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.963 |