STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEK73588.1Phosphoglycolate phosphatase. (214 aa)    
Predicted Functional Partners:
SEK35869.1
PTS system, D-glucosamine-specific IIC component.
 
 
  0.909
SEL01398.1
Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.905
SEK56026.1
PTS system, beta-glucosides-specific IIC component.
  
 
  0.893
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.801
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
   
 
  0.775
SEK73657.1
Hypothetical protein.
       0.773
SEK28322.1
Nicotinamide-nucleotide amidase.
    
  0.766
SEK73683.1
alanyl-tRNA synthetase.
  
    0.761
SEK17519.1
Cytidine deaminase.
 
 
 
  0.711
SEK72886.1
S-ribosylhomocysteine lyase /quorum-sensing autoinducer 2 (AI-2) synthesis protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
 
 
 
  0.672
Your Current Organism:
Pseudobutyrivibrio ruminis
NCBI taxonomy Id: 46206
Other names: DSM 9787, P. ruminis, strain A12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.