SEL00471.1 protein (Pseudobutyrivibrio ruminis)

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Score

SEL00471.1

RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (268 aa)

Predicted Functional Partners:

ylqF

0.888

mnmE

0.877

rsfS

0.872

rplC

0.869

rplQ

0.865

rplU

0.862

rplO

0.861

rplK

0.855

rplM

0.855

rplX

0.852

Your Current Organism:

Pseudobutyrivibrio ruminis

NCBI taxonomy Id: 46206
Other names: DSM 9787, P. ruminis, strain A12-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SEL00471.1	mnmE	SAMN02910377_02412	SAMN02910377_01745	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	0.877
SEL00471.1	rplC	SAMN02910377_02412	SAMN02910377_02111	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Large subunit ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.869
SEL00471.1	rplK	SAMN02910377_02412	SAMN02910377_01635	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.855
SEL00471.1	rplM	SAMN02910377_02412	SAMN02910377_02240	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.855
SEL00471.1	rplO	SAMN02910377_02412	SAMN02910377_02092	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.861
SEL00471.1	rplQ	SAMN02910377_02412	SAMN02910377_02082	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Large subunit ribosomal protein L17.	0.865
SEL00471.1	rplU	SAMN02910377_02412	SAMN02910377_00431	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Large subunit ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.862
SEL00471.1	rplX	SAMN02910377_02412	SAMN02910377_02100	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Large subunit ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	0.852
SEL00471.1	rsfS	SAMN02910377_02412	SAMN02910377_00425	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.872
SEL00471.1	ylqF	SAMN02910377_02412	SAMN02910377_01354	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	0.888
mnmE	SEL00471.1	SAMN02910377_01745	SAMN02910377_02412	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.	0.877
mnmE	rplC	SAMN02910377_01745	SAMN02910377_02111	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	Large subunit ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.902
mnmE	rplK	SAMN02910377_01745	SAMN02910377_01635	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.890
mnmE	rplM	SAMN02910377_01745	SAMN02910377_02240	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.915
mnmE	rplO	SAMN02910377_01745	SAMN02910377_02092	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.904
mnmE	rplQ	SAMN02910377_01745	SAMN02910377_02082	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	Large subunit ribosomal protein L17.	0.883
mnmE	rplU	SAMN02910377_01745	SAMN02910377_00431	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	Large subunit ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.907
mnmE	rplX	SAMN02910377_01745	SAMN02910377_02100	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	Large subunit ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	0.876
mnmE	rsfS	SAMN02910377_01745	SAMN02910377_00425	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.883
mnmE	ylqF	SAMN02910377_01745	SAMN02910377_01354	tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	0.897