STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFI62984.1Conserved hypothetical protein, cofD-related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (331 aa)    
Predicted Functional Partners:
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
 
  
 0.963
SFI63021.1
UPF0042 nucleotide-binding protein; Displays ATPase and GTPase activities.
  
  
 0.962
topA
DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.762
SFJ61782.1
Protein phosphatase.
  
  
 0.736
SFI62913.1
Catabolite repression HPr-like protein/phosphocarrier protein.
  
  
 0.696
SFJ42907.1
Protein phosphatase 2C.
   
  
 0.600
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
   
 0.498
SFI63093.1
HTH domain-containing protein.
       0.491
mqnE
Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
    
 0.482
mqnE-2
Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
    
 0.482
Your Current Organism:
Thermoflavimicrobium dichotomicum
NCBI taxonomy Id: 46223
Other names: ATCC 49854, Actinobifida dichotomica, DSM 44778, JCM 9688, KCTC 3667, T. dichotomicum, Thermoactinomyces dichotomica, Thermoactinomyces dichotomicus, Thermomonospora citrina, strain 114
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