node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFI86133.1 | SFJ36237.1 | SAMN05421852_102259 | SAMN05421852_10855 | DnaJ domain-containing protein. | Molecular chaperone HtpG. | 0.960 |
SFI86133.1 | SFJ36294.1 | SAMN05421852_102259 | SAMN05421852_10857 | DnaJ domain-containing protein. | Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...] | 0.834 |
SFI86133.1 | SFJ37055.1 | SAMN05421852_102259 | SAMN05421852_10886 | DnaJ domain-containing protein. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.785 |
SFI86133.1 | SFJ47840.1 | SAMN05421852_102259 | SAMN05421852_110123 | DnaJ domain-containing protein. | C-terminal, D2-small domain-containing protein, of ClpB protein. | 0.785 |
SFI86133.1 | dnaK | SAMN05421852_102259 | SAMN05421852_104168 | DnaJ domain-containing protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.936 |
SFI86133.1 | groL | SAMN05421852_102259 | SAMN05421852_1198 | DnaJ domain-containing protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.783 |
SFI86133.1 | grpE | SAMN05421852_102259 | SAMN05421852_104169 | DnaJ domain-containing protein. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.834 |
SFI86133.1 | hrcA | SAMN05421852_102259 | SAMN05421852_104170 | DnaJ domain-containing protein. | Heat-inducible transcriptional repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.726 |
SFI99462.1 | SFJ36237.1 | SAMN05421852_103168 | SAMN05421852_10855 | Protein of unknown function. | Molecular chaperone HtpG. | 0.960 |
SFI99462.1 | SFJ36294.1 | SAMN05421852_103168 | SAMN05421852_10857 | Protein of unknown function. | Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...] | 0.834 |
SFI99462.1 | SFJ37055.1 | SAMN05421852_103168 | SAMN05421852_10886 | Protein of unknown function. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.785 |
SFI99462.1 | SFJ47840.1 | SAMN05421852_103168 | SAMN05421852_110123 | Protein of unknown function. | C-terminal, D2-small domain-containing protein, of ClpB protein. | 0.785 |
SFI99462.1 | dnaK | SAMN05421852_103168 | SAMN05421852_104168 | Protein of unknown function. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.936 |
SFI99462.1 | groL | SAMN05421852_103168 | SAMN05421852_1198 | Protein of unknown function. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.783 |
SFI99462.1 | grpE | SAMN05421852_103168 | SAMN05421852_104169 | Protein of unknown function. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.834 |
SFI99462.1 | hrcA | SAMN05421852_103168 | SAMN05421852_104170 | Protein of unknown function. | Heat-inducible transcriptional repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.726 |
SFJ36237.1 | SFI86133.1 | SAMN05421852_10855 | SAMN05421852_102259 | Molecular chaperone HtpG. | DnaJ domain-containing protein. | 0.960 |
SFJ36237.1 | SFI99462.1 | SAMN05421852_10855 | SAMN05421852_103168 | Molecular chaperone HtpG. | Protein of unknown function. | 0.960 |
SFJ36237.1 | SFJ36294.1 | SAMN05421852_10855 | SAMN05421852_10857 | Molecular chaperone HtpG. | Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...] | 0.754 |
SFJ36237.1 | SFJ37055.1 | SAMN05421852_10855 | SAMN05421852_10886 | Molecular chaperone HtpG. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.787 |