STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFJ17578.12-dehydro-3-deoxygluconokinase. (316 aa)    
Predicted Functional Partners:
SFJ17601.1
2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase.
 
 
 0.986
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.931
SFJ24747.1
PTS system, fructose-specific IIC component.
  
 
 0.913
SFJ17630.1
Galactonate dehydratase.
 
  
 0.889
SFJ17546.1
DNA-binding transcriptional regulator, IclR family.
 
     0.856
SFJ61719.1
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.823
SFJ88309.1
5-deoxy-glucuronate isomerase.
  
 
 0.823
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.812
SFJ88389.1
Inosose dehydratase.
  
 
 0.772
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.768
Your Current Organism:
Thermoflavimicrobium dichotomicum
NCBI taxonomy Id: 46223
Other names: ATCC 49854, Actinobifida dichotomica, DSM 44778, JCM 9688, KCTC 3667, T. dichotomicum, Thermoactinomyces dichotomica, Thermoactinomyces dichotomicus, Thermomonospora citrina, strain 114
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