STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFJ35053.1Transcriptional pleiotropic regulator of transition state genes. (90 aa)    
Predicted Functional Partners:
SFJ30609.1
Two-component system, response regulator, stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.781
SFJ61875.1
Spore germination protein KA/spore germination protein.
  
     0.730
SFI72658.1
Spore germination protein KA.
  
     0.714
SFJ70940.1
Spore germination protein KA.
  
     0.708
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
    0.655
SFJ57765.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.652
SFJ90963.1
RNA polymerase sporulation-specific sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
     0.647
SFJ90944.1
RNA polymerase sporulation-specific sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
    0.643
SFI65943.1
Putative DeoR family transcriptional regulator, stage III sporulation protein D.
  
   
 0.607
SFI66997.1
Stage II sporulation protein R.
  
     0.605
Your Current Organism:
Thermoflavimicrobium dichotomicum
NCBI taxonomy Id: 46223
Other names: ATCC 49854, Actinobifida dichotomica, DSM 44778, JCM 9688, KCTC 3667, T. dichotomicum, Thermoactinomyces dichotomica, Thermoactinomyces dichotomicus, Thermomonospora citrina, strain 114
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