STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smcCondensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1196 aa)    
Predicted Functional Partners:
scpA
Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
 
 0.997
SFI59002.1
Carbohydrate binding domain-containing protein.
   
 
 0.990
ftsY
Fused signal recognition particle receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
   0.875
scpB
Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
 
 
 0.863
SFI57866.1
Hypothetical protein.
    
 0.826
cinA
Nicotinamide-nucleotide amidase; Belongs to the CinA family.
    
  0.798
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  0.786
SFJ71398.1
ATP-dependent DNA helicase RecQ.
  
 
 0.786
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.775
SFJ70822.1
Two-component system, NtrC family, sensor kinase.
   
  0.759
Your Current Organism:
Thermoflavimicrobium dichotomicum
NCBI taxonomy Id: 46223
Other names: ATCC 49854, Actinobifida dichotomica, DSM 44778, JCM 9688, KCTC 3667, T. dichotomicum, Thermoactinomyces dichotomica, Thermoactinomyces dichotomicus, Thermomonospora citrina, strain 114
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