STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B4102_3402Hypothetical protein; Putative endonuclease. (177 aa)    
Predicted Functional Partners:
B4102_3403
Hypothetical protein.
    
  0.776
B4102_3401
Hypothetical protein.
       0.773
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.553
B4102_3404
Hypothetical protein; Negative regulation of the defective prophage PBSX genes.
    
  0.516
mtnN
5'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.471
rsmA
Hypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
 
  0.471
B4102_1560
Adenine-specific methyltransferase.
    
 0.463
B4102_1807
Hypothetical protein SAV1869.
   
    0.459
B4102_3502
Hypothetical protein; Intein homing endonuclease-related protein.
  
    0.419
B4102_1454
Hypothetical protein; S-adenosylmethionine-dependent methyltransferase.
  
  
  0.407
Your Current Organism:
Bacillus sporothermodurans
NCBI taxonomy Id: 46224
Other names: B. sporothermodurans, CIP 104910, DSM 10599, LMG 17668, LMG 17894, LMG:17668, LMG:17894, strain M215, strain MB 581
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.