STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B4102_3452Possible tetrapyrrole methyltransferase domain / Nucleoside triphosphate pyrophosphohydrolase MazG. (486 aa)    
Predicted Functional Partners:
B4102_3451
Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 -like protein).
  
    0.827
B4102_3453
Hypothetical protein; Putative Polysaccharide biosynthesis protein YabM.
  
    0.767
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
    
  0.763
B4102_1646
Uroporphyrinogen-III methyltransferase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
    
  0.745
B4102_1694
GTP pyrophosphokinase, (p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.741
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.732
B4102_1146
Hypothetical protein; Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).
    
  0.728
B4102_2525
TPR-repeat-containing protein, putative component of Menaquinone-cytochrome C reductase.
    
  0.718
tilS
Hypoxanthine-guanine phosphoribosyltransferase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
    
 0.715
B4102_0345
Hypothetical protein; Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).
    
  0.714
Your Current Organism:
Bacillus sporothermodurans
NCBI taxonomy Id: 46224
Other names: B. sporothermodurans, CIP 104910, DSM 10599, LMG 17668, LMG 17894, LMG:17668, LMG:17894, strain M215, strain MB 581
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