| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFW96804.1 | acsA | ANA_C20360 | ANA_C20698 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.937 |
| AFW96804.1 | atpA | ANA_C20360 | ANA_C20290 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | ATP synthase F1 subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | 0.793 |
| AFW96804.1 | dhsB | ANA_C20360 | ANA_C13616 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | 0.851 |
| AFW96804.1 | hoxF | ANA_C20360 | ANA_C11899 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | Hydrogenase subunit HoxF. | 0.892 |
| AFW96804.1 | nifJ | ANA_C20360 | ANA_C11949 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | Pyruvate-flavodoxin oxidoreductase NifJ; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.951 |
| AFW96804.1 | nifJ-2 | ANA_C20360 | ANA_C13770 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.951 |
| AFW96804.1 | sdhA | ANA_C20360 | ANA_C13099 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | Succinate dehydrogenase flavoprotein subunit. | 0.662 |
| AFW96804.1 | sucC | ANA_C20360 | ANA_C10909 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | succinyl-CoA synthetase beta subunit. | 0.982 |
| AFW96804.1 | sucD | ANA_C20360 | ANA_C10910 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | succinyl-CoA synthetase alpha subunit. | 0.974 |
| acsA | AFW96804.1 | ANA_C20698 | ANA_C20360 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | 0.937 |
| acsA | dhsB | ANA_C20698 | ANA_C13616 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | 0.535 |
| acsA | nifJ | ANA_C20698 | ANA_C11949 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Pyruvate-flavodoxin oxidoreductase NifJ; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.967 |
| acsA | nifJ-2 | ANA_C20698 | ANA_C13770 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.967 |
| acsA | sdhA | ANA_C20698 | ANA_C13099 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Succinate dehydrogenase flavoprotein subunit. | 0.510 |
| acsA | sucC | ANA_C20698 | ANA_C10909 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | succinyl-CoA synthetase beta subunit. | 0.900 |
| acsA | sucD | ANA_C20698 | ANA_C10910 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | succinyl-CoA synthetase alpha subunit. | 0.886 |
| atpA | AFW96804.1 | ANA_C20290 | ANA_C20360 | ATP synthase F1 subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase. | 0.793 |
| atpA | dhsB | ANA_C20290 | ANA_C13616 | ATP synthase F1 subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | 0.778 |
| atpA | hoxF | ANA_C20290 | ANA_C11899 | ATP synthase F1 subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Hydrogenase subunit HoxF. | 0.960 |
| atpA | nifJ | ANA_C20290 | ANA_C11949 | ATP synthase F1 subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Pyruvate-flavodoxin oxidoreductase NifJ; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.538 |