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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (304 aa)    
Predicted Functional Partners:
AFW95041.1
Homoserine dehydrogenase.
  
 0.991
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.980
thrC-2
Threonine synthase.
  
 
 0.980
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.914
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.887
cysE
Serine O-acetyltransferase.
     
 0.832
cysE-2
Serine O-acetyltransferase.
     
 0.832
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.800
lysC
Aspartate kinase.
  
 
 0.776
leuC
3-isopropylmalate dehydratase large subunit; Belongs to the aconitase/IPM isomerase family.
  
  
 0.749
Your Current Organism:
Anabaena sp. 90
NCBI taxonomy Id: 46234
Other names: A. sp. 90, Anabaena circinalis 90, Anabaena sp. strain 90
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