| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hupS | hypA | ANA_C11439 | ANA_C11460 | Uptake hydrogenase small subunit, HupS. | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.666 |
| hupS | hypB | ANA_C11439 | ANA_C11459 | Uptake hydrogenase small subunit, HupS. | Hydrogenase accessory protein HypB. | 0.743 |
| hupS | hypC | ANA_C11439 | ANA_C11464 | Uptake hydrogenase small subunit, HupS. | Hydrogenase expression/formation protein HypC/HupF. | 0.805 |
| hupS | hypD | ANA_C11439 | ANA_C11463 | Uptake hydrogenase small subunit, HupS. | Hydrogenase expression/formation protein HypD. | 0.918 |
| hupS | hypE | ANA_C11439 | ANA_C11461 | Uptake hydrogenase small subunit, HupS. | Hydrogenase expression/formation protein HypE. | 0.863 |
| hupS | hypF | ANA_C11439 | ANA_C11465 | Uptake hydrogenase small subunit, HupS. | Hydrogenase maturation protein HypF. | 0.724 |
| hupS | ureG | ANA_C11439 | ANA_C13120 | Uptake hydrogenase small subunit, HupS. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.407 |
| hypA | hupS | ANA_C11460 | ANA_C11439 | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Uptake hydrogenase small subunit, HupS. | 0.666 |
| hypA | hypB | ANA_C11460 | ANA_C11459 | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase accessory protein HypB. | 0.995 |
| hypA | hypC | ANA_C11460 | ANA_C11464 | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase expression/formation protein HypC/HupF. | 0.970 |
| hypA | hypD | ANA_C11460 | ANA_C11463 | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase expression/formation protein HypD. | 0.971 |
| hypA | hypE | ANA_C11460 | ANA_C11461 | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase expression/formation protein HypE. | 0.968 |
| hypA | hypF | ANA_C11460 | ANA_C11465 | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase maturation protein HypF. | 0.961 |
| hypA | ureE | ANA_C11460 | ANA_C13118 | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.750 |
| hypA | ureF | ANA_C11460 | ANA_C13119 | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.750 |
| hypA | ureG | ANA_C11460 | ANA_C13120 | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.881 |
| hypB | hupS | ANA_C11459 | ANA_C11439 | Hydrogenase accessory protein HypB. | Uptake hydrogenase small subunit, HupS. | 0.743 |
| hypB | hypA | ANA_C11459 | ANA_C11460 | Hydrogenase accessory protein HypB. | Hydrogenase expression/synthesis protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.995 |
| hypB | hypC | ANA_C11459 | ANA_C11464 | Hydrogenase accessory protein HypB. | Hydrogenase expression/formation protein HypC/HupF. | 0.983 |
| hypB | hypD | ANA_C11459 | ANA_C11463 | Hydrogenase accessory protein HypB. | Hydrogenase expression/formation protein HypD. | 0.983 |