| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFW97139.1 | exsB | ANA_C20722 | ANA_C10446 | 6-pyruvoyl tetrahydropterin synthase. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.828 |
| AFW97139.1 | guaA | ANA_C20722 | ANA_C13684 | 6-pyruvoyl tetrahydropterin synthase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.440 |
| AFW97139.1 | queD | ANA_C20722 | ANA_C13754 | 6-pyruvoyl tetrahydropterin synthase. | Queuosine biosynthesis protein QueD. | 0.920 |
| AFW97139.1 | queE | ANA_C20722 | ANA_C13753 | 6-pyruvoyl tetrahydropterin synthase. | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.968 |
| AFW97139.1 | queF | ANA_C20722 | ANA_C11351 | 6-pyruvoyl tetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.701 |
| exsB | AFW97139.1 | ANA_C10446 | ANA_C20722 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 6-pyruvoyl tetrahydropterin synthase. | 0.828 |
| exsB | queD | ANA_C10446 | ANA_C13754 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Queuosine biosynthesis protein QueD. | 0.967 |
| exsB | queE | ANA_C10446 | ANA_C13753 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.996 |
| exsB | queF | ANA_C10446 | ANA_C11351 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.991 |
| guaA | AFW97139.1 | ANA_C13684 | ANA_C20722 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 6-pyruvoyl tetrahydropterin synthase. | 0.440 |
| guaA | queD | ANA_C13684 | ANA_C13754 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Queuosine biosynthesis protein QueD. | 0.440 |
| guaA | queE | ANA_C13684 | ANA_C13753 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.460 |
| guaA | queF | ANA_C13684 | ANA_C11351 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.475 |
| queD | AFW97139.1 | ANA_C13754 | ANA_C20722 | Queuosine biosynthesis protein QueD. | 6-pyruvoyl tetrahydropterin synthase. | 0.920 |
| queD | exsB | ANA_C13754 | ANA_C10446 | Queuosine biosynthesis protein QueD. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.967 |
| queD | guaA | ANA_C13754 | ANA_C13684 | Queuosine biosynthesis protein QueD. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.440 |
| queD | queE | ANA_C13754 | ANA_C13753 | Queuosine biosynthesis protein QueD. | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
| queD | queF | ANA_C13754 | ANA_C11351 | Queuosine biosynthesis protein QueD. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.756 |
| queE | AFW97139.1 | ANA_C13753 | ANA_C20722 | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 6-pyruvoyl tetrahydropterin synthase. | 0.968 |
| queE | exsB | ANA_C13753 | ANA_C10446 | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.996 |