| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFW93725.1 | AFW95083.1 | ANA_C10933 | ANA_C12352 | DnaJ-class molecular chaperone. | Heat shock protein 90. | 0.901 |
| AFW93725.1 | clpB | ANA_C10933 | ANA_C12346 | DnaJ-class molecular chaperone. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.560 |
| AFW93725.1 | clpB-2 | ANA_C10933 | ANA_C13351 | DnaJ-class molecular chaperone. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.537 |
| AFW93725.1 | dnaK-2 | ANA_C10933 | ANA_C20366 | DnaJ-class molecular chaperone. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.934 |
| AFW93725.1 | groEL | ANA_C10933 | ANA_C11745 | DnaJ-class molecular chaperone. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.637 |
| AFW93725.1 | groL | ANA_C10933 | ANA_C20021 | DnaJ-class molecular chaperone. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.664 |
| AFW93725.1 | groS | ANA_C10933 | ANA_C20020 | DnaJ-class molecular chaperone. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.609 |
| AFW93725.1 | grpE | ANA_C10933 | ANA_C13199 | DnaJ-class molecular chaperone. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.775 |
| AFW95083.1 | AFW93725.1 | ANA_C12352 | ANA_C10933 | Heat shock protein 90. | DnaJ-class molecular chaperone. | 0.901 |
| AFW95083.1 | clpB | ANA_C12352 | ANA_C12346 | Heat shock protein 90. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.694 |
| AFW95083.1 | clpB-2 | ANA_C12352 | ANA_C13351 | Heat shock protein 90. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.694 |
| AFW95083.1 | dnaJ | ANA_C12352 | ANA_C13197 | Heat shock protein 90. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.964 |
| AFW95083.1 | dnaJ-2 | ANA_C12352 | ANA_C20367 | Heat shock protein 90. | Chaperone protein DnaJ. | 0.901 |
| AFW95083.1 | dnaK-2 | ANA_C12352 | ANA_C20366 | Heat shock protein 90. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.922 |
| AFW95083.1 | groEL | ANA_C12352 | ANA_C11745 | Heat shock protein 90. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.865 |
| AFW95083.1 | groL | ANA_C12352 | ANA_C20021 | Heat shock protein 90. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.880 |
| AFW95083.1 | groS | ANA_C12352 | ANA_C20020 | Heat shock protein 90. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.859 |
| AFW95083.1 | grpE | ANA_C12352 | ANA_C13199 | Heat shock protein 90. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.711 |
| clpB | AFW93725.1 | ANA_C12346 | ANA_C10933 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | DnaJ-class molecular chaperone. | 0.560 |
| clpB | AFW95083.1 | ANA_C12346 | ANA_C12352 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock protein 90. | 0.694 |
STRING v12.5 is now available!
