STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GA22038ATP-dependent RNA helicase SUV3 homolog, mitochondrial; Major helicase player in mitochondrial RNA metabolism and maintenance. Likely component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Regulates mRNA stability and is required for the correct processing and maturation of mitochondrial transcripts. (762 aa)    
Predicted Functional Partners:
Q297C3
Exosome complex exonuclease DIS3/RRP44.
   
 
 0.875
DpseGA14227
RNB domain-containing protein; Belongs to the RNR ribonuclease family.
   
 
 0.875
Q290G0
Uncharacterized protein.
   
  
 0.840
Q29BB6
Polyribonucleotide nucleotidyltransferase.
   
 
 0.735
B5DW65
ATP-dependent RNA helicase DDX18/HAS1.
   
 
 0.688
DpseGA21960
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 
 0.619
atp6
ATP synthase subunit a.
      
 0.614
DpseGA18324
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
 
 0.608
Q298G7
ATP-dependent RNA helicase.
    
 
 0.599
DpseGA10992
Uncharacterized protein.
   
  
 0.560
Your Current Organism:
Drosophila pseudoobscura
NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura
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