STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DpseGA11764Uncharacterized protein. (873 aa)    
Predicted Functional Partners:
A0A0R3NL21
Uncharacterized protein, isoform B.
    
 0.624
DpseGA21600
Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.576
Q291E9
Structural maintenance of chromosome 2.
   
 
 0.543
SAK
Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the mother centriole cylinder, using mother centriole as a platform, leading to the recruitment of centriole biogenesis proteins such as sas-6. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Centrosome amplification following overexpression can initiate tumorigenesis, highlighting [...]
   
 0.501
Q295U1
Uncharacterized protein.
   
 0.478
DpseGA19730
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.478
DpseGA25963
Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
   
  
 0.468
Q295L2
Serine/threonine-protein kinase TTK/MPS1.
   
   0.460
DpseGA25921
Structural maintenance of chromosomes protein.
   
 
 0.446
B5E0B4
Uncharacterized protein, isoform A.
   
  
 0.444
Your Current Organism:
Drosophila pseudoobscura
NCBI taxonomy Id: 46245
Other names: D. pseudoobscura pseudoobscura, Drosophila pseudoobscura pseudoobscura
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.