Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ANN76019.15'-3'-deoxyribonucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)    
Predicted Functional Partners:
ANN77065.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family.
  
  
  0.936
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
 
 0.931
ANN80151.1
NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.914
ANN80696.1
Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
  
  
  0.913
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
 
 0.904
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.903
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
  0.903
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.903
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.903
ANN76211.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
    
  0.902
Your Current Organism:
Bordetella flabilis
NCBI taxonomy Id: 463014
Other names: B. flabilis, Bordetella flabilis Vandamme et al. 2015, Bordetella sp. AU10664, CCUG 56827, LMG 28642, LMG:28642, strain AU10664
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