Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANN80161.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (485 aa)    
Predicted Functional Partners:
ANN77789.1
4-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.919
ANN76264.1
4-hydroxy-2-oxovalerate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.907
ANN77922.1
Catalyzes the retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate to pyruvate and lactaldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.907
ANN78502.1
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.907
ANN77286.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.905
ANN80141.1
CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CoA-transferase III family.
     
  0.900
ANN75994.1
CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CoA-transferase III family.
     
  0.900
ANN77904.1
CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CoA-transferase III family.
     
  0.900
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.862
ANN77054.1
2-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.858
Your Current Organism:
Bordetella flabilis
NCBI taxonomy Id: 463014
Other names: B. flabilis, Bordetella flabilis Vandamme et al. 2015, Bordetella sp. AU10664, CCUG 56827, LMG 28642, LMG:28642, strain AU10664
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