Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANN80227.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (786 aa)    
Predicted Functional Partners:
ANN76445.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.960
ANN80228.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.958
ANN76446.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.953
ANN79015.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial histone-like protein family.
  
     0.739
ANN79561.1
Histone; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.679
ANN78684.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.669
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.597
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
 
 0.597
ANN76149.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.552
ANN78264.1
Flagellar assembly protein FliT; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.534
Your Current Organism:
Bordetella flabilis
NCBI taxonomy Id: 463014
Other names: B. flabilis, Bordetella flabilis Vandamme et al. 2015, Bordetella sp. AU10664, CCUG 56827, LMG 28642, LMG:28642, strain AU10664
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