Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
crcBFluoride ion transporter CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (125 aa)    
Predicted Functional Partners:
ANN77257.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.720
ANN77642.1
Multidrug efflux RND transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.676
ANN80093.1
MATE family efflux transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.675
ANN77142.1
MATE family efflux transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.662
ANN80356.1
Nodulation protein NodJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.633
apaG
Co2+/Mg2+ efflux protein ApaG; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.625
ANN76879.1
DNA alkylation response protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.602
ANN79425.1
Molybdenum cofactor biosynthesis protein MoaE; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.546
ANN77621.1
Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.492
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.458
Your Current Organism:
Bordetella flabilis
NCBI taxonomy Id: 463014
Other names: B. flabilis, Bordetella flabilis Vandamme et al. 2015, Bordetella sp. AU10664, CCUG 56827, LMG 28642, LMG:28642, strain AU10664
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