| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANN77621.1 | ANN77715.1 | BAU07_11340 | BAU07_11890 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.599 |
| ANN77621.1 | ANN77716.1 | BAU07_11340 | BAU07_11895 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.972 |
| ANN77621.1 | ANN78529.1 | BAU07_11340 | BAU07_16700 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
| ANN77621.1 | ANN80131.1 | BAU07_11340 | BAU07_00770 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.692 |
| ANN77621.1 | argA | BAU07_11340 | BAU07_09220 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amino-acid N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. ArgA subfamily. | 0.579 |
| ANN77621.1 | argB | BAU07_11340 | BAU07_24115 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.628 |
| ANN77621.1 | argH | BAU07_11340 | BAU07_11330 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.526 |
| ANN77621.1 | glnD | BAU07_11340 | BAU07_15120 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional uridylyltransferase/uridylyl-removing protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.982 |
| ANN77621.1 | glnE | BAU07_11340 | BAU07_17540 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional glutamine synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] | 0.552 |
| ANN77621.1 | nadE | BAU07_11340 | BAU07_11335 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.806 |
| ANN77715.1 | ANN77621.1 | BAU07_11890 | BAU07_11340 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.599 |
| ANN77715.1 | ANN77716.1 | BAU07_11890 | BAU07_11895 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.808 |
| ANN77715.1 | ANN78529.1 | BAU07_11890 | BAU07_16700 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.600 |
| ANN77715.1 | ANN80131.1 | BAU07_11890 | BAU07_00770 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.969 |
| ANN77715.1 | argA | BAU07_11890 | BAU07_09220 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amino-acid N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. ArgA subfamily. | 0.466 |
| ANN77715.1 | glnD | BAU07_11890 | BAU07_15120 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional uridylyltransferase/uridylyl-removing protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.482 |
| ANN77715.1 | glnE | BAU07_11890 | BAU07_17540 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional glutamine synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] | 0.792 |
| ANN77715.1 | nadE | BAU07_11890 | BAU07_11335 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.503 |
| ANN77716.1 | ANN77621.1 | BAU07_11895 | BAU07_11340 | PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.972 |
| ANN77716.1 | ANN77715.1 | BAU07_11895 | BAU07_11890 | PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.808 |
