Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANN78401.1Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)    
Predicted Functional Partners:
ANN78402.1
MFS transporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
ANN78403.1
ABC-F family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.660
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
  0.569
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 
  0.519
ANN80183.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
  0.500
ANN76323.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.500
ANN79988.1
Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
     
  0.500
rsmG
16S rRNA (guanine(527)-N(7))-methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
 
     0.466
ANN80438.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.417
ANN80595.1
Magnesium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.417
Your Current Organism:
Bordetella flabilis
NCBI taxonomy Id: 463014
Other names: B. flabilis, Bordetella flabilis Vandamme et al. 2015, Bordetella sp. AU10664, CCUG 56827, LMG 28642, LMG:28642, strain AU10664
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