STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANN78783.1Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)    
Predicted Functional Partners:
ANN78223.1
3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HIBADH-related family.
 
 
 0.944
ANN77042.1
2-methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 0.926
ANN75767.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.923
ANN76165.1
Omega amino acid--pyruvate aminotransferase; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.921
ANN79929.1
acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.920
ANN76696.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.917
ANN78879.1
3-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.914
ANN78746.1
AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.910
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.910
ANN78779.1
propionate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.910
Your Current Organism:
Bordetella flabilis
NCBI taxonomy Id: 463014
Other names: B. flabilis, Bordetella flabilis Vandamme et al. 2015, Bordetella sp. AU10664, CCUG 56827, LMG 28642, LMG:28642, strain AU10664
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