STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaAHydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family. (432 aa)    
Predicted Functional Partners:
Lgor_0388
Diphosphomevalonate decarboxylase.
 
 
 0.935
Lgor_0389
Mevalonate kinase.
 
 0.925
Lgor_0379
Hypothetical protein.
  
 0.923
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.797
yngG
hydroxymethylglutaryl-CoA lyase.
    
  0.679
bphI
4-hydroxy-2-oxovalerate aldolase.
    
  0.552
pksL_4
Polyketide synthase.
     
 0.466
ispB
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.442
ispA
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.442
Lgor_2446
Sterol desaturase-related protein.
   
  
 0.427
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.