Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
dtpA_4Hypothetical protein. (500 aa)    
Predicted Functional Partners:
iraA
Small-molecule methyltransferase IraA.
     
 0.786
Lgor_2889
Zinc-iron permease (ZIP) family metal cation transporter.
  
 
 
 0.609
lysP
Amino acid (lysine) permease.
  
     0.601
yveA_3
Amino acid permease.
  
 
   0.564
lly
4-hydroxyphenylpyruvate dioxygenase.
 
   
 0.476
yveA_1
Amino acid permease.
  
 
   0.451
gadC_3
Amino acid antiporter.
  
 
   0.435
proA
Zinc metalloproteinase precursor; Extracellular zinc metalloprotease.
  
   
 0.425
yveA_2
Amino acid permease family protein.
  
 
   0.425
ppnK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
  0.416
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
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