| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lgor_2029 | glyA | Lgor_2029 | Lgor_1925 | Phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.914 |
| Lgor_2029 | metB | Lgor_2029 | Lgor_1903 | Phosphoserine phosphatase. | Cystathionine beta-lyase. | 0.496 |
| Lgor_2029 | pssA | Lgor_2029 | Lgor_0053 | Phosphoserine phosphatase. | CDP-diacylglycerol-serine O-phosphatidyltransferase (phosphatidylserine synthase); Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.862 |
| Lgor_2029 | sdhL | Lgor_2029 | Lgor_0411 | Phosphoserine phosphatase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.878 |
| Lgor_2029 | tdcB | Lgor_2029 | Lgor_1110 | Phosphoserine phosphatase. | L-threonine dehydratase catabolic TdcB. | 0.611 |
| Lgor_2029 | trpA | Lgor_2029 | Lgor_1444 | Phosphoserine phosphatase. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.861 |
| Lgor_2029 | trpB | Lgor_2029 | Lgor_1443 | Phosphoserine phosphatase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.878 |
| budB | sdhL | Lgor_0535 | Lgor_0411 | Acetolactate synthase; Belongs to the TPP enzyme family. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.713 |
| budB | tdcB | Lgor_0535 | Lgor_1110 | Acetolactate synthase; Belongs to the TPP enzyme family. | L-threonine dehydratase catabolic TdcB. | 0.891 |
| gcvT | glyA | Lgor_0798 | Lgor_1925 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.999 |
| gcvT | sdhL | Lgor_0798 | Lgor_0411 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.708 |
| gcvT | tdcB | Lgor_0798 | Lgor_1110 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | L-threonine dehydratase catabolic TdcB. | 0.516 |
| gcvT | trpA | Lgor_0798 | Lgor_1444 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.415 |
| gloA | sdhL | Lgor_2978 | Lgor_0411 | Lactoylglutathione lyase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.861 |
| gloA | tdcB | Lgor_2978 | Lgor_1110 | Lactoylglutathione lyase. | L-threonine dehydratase catabolic TdcB. | 0.623 |
| gloA | trpA | Lgor_2978 | Lgor_1444 | Lactoylglutathione lyase. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.861 |
| gloA | trpB | Lgor_2978 | Lgor_1443 | Lactoylglutathione lyase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.870 |
| glyA | Lgor_2029 | Lgor_1925 | Lgor_2029 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase. | 0.914 |
| glyA | gcvT | Lgor_1925 | Lgor_0798 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| glyA | pssA | Lgor_1925 | Lgor_0053 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | CDP-diacylglycerol-serine O-phosphatidyltransferase (phosphatidylserine synthase); Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.861 |
