STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lgor_0427Fumarylacetoacetate hydrolase. (327 aa)    
Predicted Functional Partners:
Lgor_0428
Glutathione S-transferase (maleylacetoacetate isomerase).
 
 
 0.982
lly
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.921
hmgA
Homogentisate 1,2-dioxygenase.
 
 
 0.905
hpcD
5-carboxymethyl-2-hydroxymuconate Delta-isomerase.
  
 
 0.755
phhA
Phenylalanine-4-hydroxylase.
 
  
 0.685
bphI
4-hydroxy-2-oxovalerate aldolase.
    
  0.663
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.638
sdhA_2
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.627
Lgor_2805
NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
  
  0.616
fadH
2,4-dienoyl-CoA reductase.
    
 0.612
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
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