| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Hgd | acsB_2 | Lgor_0818 | Lgor_0817 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.926 |
| Hgd | echA8_2 | Lgor_0818 | Lgor_1244 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | enoyl-CoA hydratase. | 0.998 |
| Hgd | fadB | Lgor_0818 | Lgor_1484 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.823 |
| Hgd | mmsA | Lgor_0818 | Lgor_0819 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | 0.989 |
| Hgd | odp | Lgor_0818 | Lgor_3169 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Branched-chain alpha-keto acid dehydrogenase subunit E2. | 0.864 |
| Hgd | paaF | Lgor_0818 | Lgor_1243 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | enoyl-CoA hydratase. | 0.753 |
| Hgd | prpC | Lgor_0818 | Lgor_3202 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.872 |
| Hgd | pta_1 | Lgor_0818 | Lgor_3222 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Phosphate acetyl/butaryl transferase. | 0.877 |
| Hgd | yfcX | Lgor_0818 | Lgor_3141 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.823 |
| Hgd | ywdH | Lgor_0818 | Lgor_2077 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.875 |
| acsB_2 | Hgd | Lgor_0817 | Lgor_0818 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.926 |
| acsB_2 | echA8_2 | Lgor_0817 | Lgor_1244 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | enoyl-CoA hydratase. | 0.438 |
| acsB_2 | fadB | Lgor_0817 | Lgor_1484 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.664 |
| acsB_2 | mmsA | Lgor_0817 | Lgor_0819 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | 0.836 |
| acsB_2 | odp | Lgor_0817 | Lgor_3169 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Branched-chain alpha-keto acid dehydrogenase subunit E2. | 0.614 |
| acsB_2 | paaF | Lgor_0817 | Lgor_1243 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | enoyl-CoA hydratase. | 0.429 |
| acsB_2 | prpC | Lgor_0817 | Lgor_3202 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.697 |
| acsB_2 | pta_1 | Lgor_0817 | Lgor_3222 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphate acetyl/butaryl transferase. | 0.807 |
| acsB_2 | yfcX | Lgor_0817 | Lgor_3141 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.664 |
| acsB_2 | ywdH | Lgor_0817 | Lgor_2077 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.639 |
