Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
fixL_1Two-component sensor histidine kinase. (473 aa)    
Predicted Functional Partners:
gmr_2
Regulatory protein (GGDEF domain).
 
 
 0.974
arcB_4
Sensory histidine-kinase / response regulator.
 
 0.935
arcB_1
Sensory box histidine kinase/response regulator.
 
 0.932
letS_2
Legionella transmission sensor LetS.
 
 0.891
letS_1
Legionella transmission sensor LetS.
 
 
 0.868
dosC_1
Regulatory protein (GGDEF, PAS, PAC domains).
 
 
 0.864
Lgor_1045
FIST N domain protein.
 
     0.854
cph1_2
Two-component sensor histidine kinase.
 
 
 0.852
dosC_3
Regulatory protein (GGDEF domain).
 
 
 0.791
cph2_5
Regulatory protein (GGDEF and EAL domains).
   
 0.789
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
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