STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdcPyruvate decarboxylase. (560 aa)    
Predicted Functional Partners:
Lgor_0721
Transmembrane protein (fibronectin III domain and Gp5 C-terminal repeat).
  
  
 0.799
pdhB_1
Pyruvate/2-oxoglutarate dehydrogenase subunit E1.
     
 0.780
prpB
2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
    
 0.732
ilvE
Aminodeoxychorismate lyase.
    
 0.729
rmlA1
Nucleotidyltransferase.
   
  0.720
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
   
 
 0.707
frmA
Alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
     
 0.706
Lgor_1278
Hypothetical protein.
  
     0.685
mdh_2
Alcohol dehydrogenase.
    
 0.674
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
   
 
 0.668
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
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