| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| arcB_1 | arcB_4 | Lgor_2932 | Lgor_2075 | Sensory box histidine kinase/response regulator. | Sensory histidine-kinase / response regulator. | 0.999 |
| arcB_1 | artJ_1 | Lgor_2932 | Lgor_1171 | Sensory box histidine kinase/response regulator. | Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family. | 0.759 |
| arcB_1 | glnE | Lgor_2932 | Lgor_1170 | Sensory box histidine kinase/response regulator. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.647 |
| arcB_1 | guaA | Lgor_2932 | Lgor_1544 | Sensory box histidine kinase/response regulator. | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.670 |
| arcB_4 | arcB_1 | Lgor_2075 | Lgor_2932 | Sensory histidine-kinase / response regulator. | Sensory box histidine kinase/response regulator. | 0.999 |
| arcB_4 | artJ_1 | Lgor_2075 | Lgor_1171 | Sensory histidine-kinase / response regulator. | Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family. | 0.759 |
| arcB_4 | glnE | Lgor_2075 | Lgor_1170 | Sensory histidine-kinase / response regulator. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.647 |
| arcB_4 | guaA | Lgor_2075 | Lgor_1544 | Sensory histidine-kinase / response regulator. | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.670 |
| artJ_1 | arcB_1 | Lgor_1171 | Lgor_2932 | Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family. | Sensory box histidine kinase/response regulator. | 0.759 |
| artJ_1 | arcB_4 | Lgor_1171 | Lgor_2075 | Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family. | Sensory histidine-kinase / response regulator. | 0.759 |
| artJ_1 | glnE | Lgor_1171 | Lgor_1170 | Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.556 |
| bcp-2 | glnE | Lgor_0997 | Lgor_1170 | Bacterioferritin comigratory protein. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.450 |
| fadH | glnA | Lgor_1659 | Lgor_2746 | 2,4-dienoyl-CoA reductase. | Glutamine synthetase. | 0.620 |
| fadH | glnE | Lgor_1659 | Lgor_1170 | 2,4-dienoyl-CoA reductase. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.452 |
| fadH | guaA | Lgor_1659 | Lgor_1544 | 2,4-dienoyl-CoA reductase. | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.976 |
| glnA | fadH | Lgor_2746 | Lgor_1659 | Glutamine synthetase. | 2,4-dienoyl-CoA reductase. | 0.620 |
| glnA | glnD | Lgor_2746 | Lgor_1548 | Glutamine synthetase. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.543 |
| glnA | glnE | Lgor_2746 | Lgor_1170 | Glutamine synthetase. | Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] | 0.763 |
| glnA | glnK | Lgor_2746 | Lgor_0088 | Glutamine synthetase. | Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family. | 0.685 |
| glnA | guaA | Lgor_2746 | Lgor_1544 | Glutamine synthetase. | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.869 |
