STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slyA_2Transcriptional regulator, MarR family. (156 aa)    
Predicted Functional Partners:
Lgor_1218
Hypothetical protein.
 
     0.929
Lgor_0655
acyl-CoA synthetase.
  
 
 0.641
cph2_5
Regulatory protein (GGDEF and EAL domains).
  
  
 0.563
birA
biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.494
arcB_4
Sensory histidine-kinase / response regulator.
  
  
 0.426
arcB_1
Sensory box histidine kinase/response regulator.
  
  
 0.426
letS_1
Legionella transmission sensor LetS.
  
  
 0.425
gmr_2
Regulatory protein (GGDEF domain).
   
  
 0.424
ycgG_2
Signal transduction protein (EAL/GGDEF domain protein).
  
    0.420
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.