| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lgor_1779 | hipA | Lgor_1779 | Lgor_1778 | Polysaccharide deacetylase. | HipA protein, DNA binding regulator. | 0.455 |
| Lgor_1779 | hipB | Lgor_1779 | Lgor_1777 | Polysaccharide deacetylase. | Putative DNA-binding transcriptional regulator. | 0.455 |
| aroA | aroE | Lgor_2691 | Lgor_0941 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.978 |
| aroA | hipB | Lgor_2691 | Lgor_1777 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative DNA-binding transcriptional regulator. | 0.416 |
| aroA | ndk | Lgor_2691 | Lgor_3180 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.643 |
| aroE | aroA | Lgor_0941 | Lgor_2691 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.978 |
| aroE | hipB | Lgor_0941 | Lgor_1777 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Putative DNA-binding transcriptional regulator. | 0.416 |
| gad_1 | hipA | Lgor_1776 | Lgor_1778 | Guanine aminohydrolase. | HipA protein, DNA binding regulator. | 0.461 |
| gad_1 | hipB | Lgor_1776 | Lgor_1777 | Guanine aminohydrolase. | Putative DNA-binding transcriptional regulator. | 0.484 |
| glmU | hipB | Lgor_3067 | Lgor_1777 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Putative DNA-binding transcriptional regulator. | 0.416 |
| glmU | nadE | Lgor_3067 | Lgor_1912 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Glutamine dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.409 |
| hipA | Lgor_1779 | Lgor_1778 | Lgor_1779 | HipA protein, DNA binding regulator. | Polysaccharide deacetylase. | 0.455 |
| hipA | gad_1 | Lgor_1778 | Lgor_1776 | HipA protein, DNA binding regulator. | Guanine aminohydrolase. | 0.461 |
| hipA | hipB | Lgor_1778 | Lgor_1777 | HipA protein, DNA binding regulator. | Putative DNA-binding transcriptional regulator. | 0.948 |
| hipB | Lgor_1779 | Lgor_1777 | Lgor_1779 | Putative DNA-binding transcriptional regulator. | Polysaccharide deacetylase. | 0.455 |
| hipB | aroA | Lgor_1777 | Lgor_2691 | Putative DNA-binding transcriptional regulator. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.416 |
| hipB | aroE | Lgor_1777 | Lgor_0941 | Putative DNA-binding transcriptional regulator. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.416 |
| hipB | gad_1 | Lgor_1777 | Lgor_1776 | Putative DNA-binding transcriptional regulator. | Guanine aminohydrolase. | 0.484 |
| hipB | glmU | Lgor_1777 | Lgor_3067 | Putative DNA-binding transcriptional regulator. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.416 |
| hipB | hipA | Lgor_1777 | Lgor_1778 | Putative DNA-binding transcriptional regulator. | HipA protein, DNA binding regulator. | 0.948 |
